The primal blueprint: how CamMed mimics evolution to reinvent self-amplifying RNA
CamMed CEO Dr. Ahmet Can Berkyurek on an AI-discovered, single-protein replicase drawn from biology's most ancient machinery — and his case for building it in the UK
Clene Nanomedicine's ALS drug is a gold nanocrystal you drink. It missed its primary endpoint. The FDA is still listening.
CEO Rob Etherington and chief scientist Mark Mortenson on the bioenergetic thesis behind CNM-Au8, the HEALEY data, and five meetings with the agency.
The sugar layer biotech forgot - and why Anomer Bio thinks small molecules can finally drug it
Co-founder and CEO Sophie James on modified monosaccharides, intracellular glycan processing, and a rare-disease-first route into fibrosis, oncology, and Alzheimer's.
Slone Partners’ Leslie Loveless on the post-boom talent reset in biopharma
Biopharma’s boom-era org charts are giving way to leaner, faster operating models. Slone Partners CEO, Leslie Loveless, says the edge now goes to pragmatic builders: “The companies that win right now are hiring leaders who can do more with less.”
A world-expert in Stargardt disease has developed a pill to slow vision loss: why Tinlarebant could win FDA approval
After years studying Stargardt’s natural history, Belite Bio’s Dr. Hendrik Scholl is championing Tinlarebant as a practical early intervention - “Intervention is simply one pill a day - and we are able to slow down the progression of disease by more than one-third.”
Belite Bio concludes phase 3 Stargardt trials with nearly 40% retinal cell preservation
Belite is positioning Tinlarebant for regulatory submission after Phase 3 Stargardt data, emphasizing the long-term safety burden of a systemic, lifelong oral therapy: “For a lifelong treatment, the safety bar is about as high as it gets.”
Why Flatiron is betting on data quality, not hype, to power the next era of cancer care
With global oncology scale and nearly 2,000 scientific publications, Flatiron Health is positioning itself as the industry’s most trusted evidence partner by pairing AI-driven speed with uncompromising scientific rigor. “We don’t chase hype. We build trust, and in healthcare that’s non-negotiable.”
“Efficacy with safety”: the north star behind Outpace’s next-gen engineered cell therapies
Outpace Bio is using AI-powered protein design to build “software and hardware” into engineered cells aimed at durable solid-tumor responses. For CEO Marc Lajoie, “efficacy is still the fundamental problem that needs to be solved - efficacy and safety.”
From diagnostics to drug development: Scipher Medicine’s three-track strategy for high-impact immunology
As Scipher expands from predictive diagnostics into drug development, CEO Reginald Seeto stresses that technology must drive real clinical decisions: ‘You’ve got to bring technology to the point of greatest impact - otherwise even great innovations never get progressed.’
Why Novellia thinks the best biopharma data strategy starts with patients, not pipelines
“Everything that’s good for patients delivers extraordinary value for biopharma - that overlap is the entire company,” says Shashi Shankar, CEO. From symptom tracking to AI-driven normalization, Novellia builds patient-first data infrastructure that scales into biopharma-grade intelligence.
Mark Lappe’s lean biotech model: smaller teams, bigger wins
Inhibrx has built its drug discovery engine around tight, focused teams. The philosophy is simple: “We’re best when we’re smaller. When teams get too big, they stop innovating,” shaping how programs are advanced or spun out.
The lab-data marketplace powering precision medicine’s next wave
As pharma’s demand for real-time lab intelligence accelerates, Prognos Health is leaning in - and after six or seven years of building, the company now sees “a real path to delivering 20 billion health insights by 2050”, says CEO Sundeep Bhan.
Biotech's new superstructure: Vivodyne's bid to turn human tissues into scalable, searchable data
Vivodyne’s automated human-testing platform aims to deliver unprecedented scale, reproducibility, and biological fidelity in preclinical drug testing - powered by patient-derived tissues that “already know the instructions,” as CEO Andrei Georgescu puts it.
Inside Fabian Gerlinghaus' Cellares and their $380M push to automate cell therapy manufacturing
With Bridgewater online and global facilities underway, Cellares is moving from platform development to commercial execution. CEO Fabian Gerlinghaus says, “Our factories can produce as many therapies as ten manual facilities - with just ten percent of the people.”
Why Allucent says its global footprint is now a competitive edge in early-stage trials
Paula Brown Stafford argues that real differentiation now comes from pairing global operations with smart, disciplined innovation. “We're adding AI as a teammate, but we still need our team to have their own expertise to ask the right questions.”
Building for zero failure: How 4G Clinical is redefining trial supply management
At 4G Clinical, David Kelleher articulates a leadership philosophy built on precision, flexibility, and the belief that execution failures in trials carry real human consequences: “We will never mis-randomize, stock out, miss dose, or compromise the blind.”