Kim Brown, CEO, Compass Biomedical | Onyx Live | ISCT Dublin 2026
Everyone watches the final cell therapy – far fewer watch what the cells are grown in. Compass Biomedical's Kim Brown on why culture media quietly shapes the product.
Everyone watches the final cell therapy – far fewer watch what the cells are grown in. Compass Biomedical's Kim Brown on why culture media quietly shapes the product.
Cell and gene therapy can get treatments approved – scaling them is the hard part. Cellular Origins' Jason Jones on automating manufacturing to reach 100,000 patients a year.
Exosomes are "cell therapy without the cells" – and University of Miami's Dimitrios Kouroupis sees these cell-free vesicles reshaping musculoskeletal medicine.
Fewer than 10% of eligible CAR-T patients ever get treated. Trenchant BioSystems CEO Jon Ellis says the bottleneck is no longer the science – it's manufacturing.
Most cell therapies arrive at the patient frozen – and BioLife Solutions CTO Sean Werner says the field still treats what happens after manufacturing as an afterthought.
Most of cell therapy fixates on the cell's target. MPC Therapeutics' Augustin de Bettignies says its metabolism — what it burns during manufacturing — matters just as much.
Most cell therapies don't fail at the finish line – they fail at the start, says iPSC consultant Stephen Sullivan. Why early decisions decide late outcomes.
The cell and gene therapy tools companies that scale aren't always the ones with the best technology, says i5 BioPartners' Jeff Galecke – they're the ones that can tell a clear story.
Great science isn't enough to get funded, says investor Sven Kili – only great medicines are. Inside the CGT funding squeeze, and what specialist VCs actually screen for.
Nine years after Kymriah, the first ever CAR-T cell therapy, was approved, around 10,000 patients have been treated. Inside CAR-T’s next decade with co-inventor Bruce Levine.
Cell and gene therapy is having its golden age, says ISCT President Miguel Forte – and is still in adolescence. Inside the field's reshaping priorities.
AviadoBio is running three CNS gene therapy programs and recently announced a capsid partnership with Apertura to take its silencing platform from rare disease into Alzheimer's.
In cell and gene therapy, the science is rarely the bottleneck – making it at scale is. Inside the Bayer–Charité incubator betting on Berlin to fix that.
Heart disease kills more people than every cancer combined. Inside Tenaya's bet that the precision-medicine playbook oncology pioneered will work on the heart, too.
More and more cell types cannot be frozen anymore. If you think about organoids, mixed cultures, artificial tissues – all of those require warm chain logistics.
In a funding-constrained biotech market, most early-stage teams still try to reinvent the AAV and advanced-therapy CMC playbooks the industry has already solved a dozen times over.